Re-engineering of HKU4 to cross species
from bat to human
“...re-engineered HKU4 spike, aiming to build its capacity to mediate viral entry into human cells.”
“To this end, we introduced two single mutations...mutations in these motifs in coronavirus spikes have demonstrated dramatic effects on viral entry into human cells.”
Shi Zhengli, A.K.A. "The Bat Lady", Director of the Centre for Emergence of Infectious Disease and Biosafety at the Wuhan Institute of Virology, a Biosafety Level Four Biocontainment Lab
An open debate on SARS-CoV-2's proximal origin is long overdue. February 7, 2021.
Steve Hilton investigates origin of COVID-19, links to US commissioned research
Jan. 25, 2021 - 15:49 - 'The Next Revolution' host breaks down the evidence surrounding the origins of COVID-19.
Gain of Function Research
With a paper trail from China's bat caves to North Carolina, to increase infectivity and virulence of virus. Documents tracking the virus back to Wuhan with $3.5 million from U.S. National Institute of Health funding.
"There are viruses that exist in bat species, preprogrammed to jump between species and replicate just fine in humans. We had no access to the viruses in China, all we had was access to the sequence."
min 2:15 - 2:30
Dr. Ralph Baric
Professor of Microbiology and Immunology
University of North Carolina
mRNA Transcription Capacity
Evidence shows that SARS-CoV-2 spike protein can Integrate into human DNA.
Image to the right shows mRNA getting into brain cells
Using the Reverse Transcriptase (RT) found in human platelets, CD4 (Helper Cells) and other cells carrying Long Interspersed Nuclear Elements (LINE-1); or by the HIV-RT. Research has shown that SARS-CoV-2 mRNA can insert itself into human DNA
LINE-1 averages 6,000 base pairs (bp) and comprises approximately 17% of human DNA
80 -100 of these LINE-1 segments are known to retro transpose leading to insertions, deletions, and rearrangement of genetic material.
Presence of Prion-like
Prion-like domains are critical to SARS-CoV-2 virulence. Prions are associated with "Mad Cow Disease" and neuromuscular movement disorders seen in Parkinson's Disease and Alzheimer's.
Creutzfeldt–Jakob disease (CJD), also known as subacute spongiform encephalopathy or neurocognitive disorder due to prion disease, is a fatal degenerative brain disorder. Early symptoms include memory problems, behavioral changes, poor coordination, and visual disturbances. Later symptoms include dementia, involuntary movements, blindness, weakness, and coma. About 70% of people die within a year of diagnosis.